Selective V(1a) agonism attenuates vascular dysfunction and fluid accumulation in ovine severe sepsis

Vasopressin analogs are used as a supplement to norepinephrine in septic shock. The isolated effects of vasopressin agonists on sepsis-induced vascular dysfunction, however, remain controversial. Because V(2)-receptor stimulation induces vasodilation and procoagulant effects, a higher V(1a)- versus...

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Autors principals: Rehberg, Sebastian, Yamamoto, Yusuke, Sousse, Linda, Bartha, Eva, Jonkam, Collette, Hasselbach, Anthony K., Traber, Lillian D., Cox, Robert A., Westphal, Martin, Enkhbaatar, Perenlei, Traber, Daniel L.
Format: Artigo
Idioma:Inglês
Publicat: American Physiological Society 2012
Matèries:
Integrative Cardiovascular Physiology and Pathophysiology
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3517638/
https://ncbi.nlm.nih.gov/pubmed/22961865
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpheart.00390.2012
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