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Targeting Fatty Acid Binding Protein (FABP) Anandamide Transporters – A Novel Strategy for Development of Anti-Inflammatory and Anti-Nociceptive Drugs

Fatty acid binding proteins (FABPs), in particular FABP5 and FABP7, have recently been identified by us as intracellular transporters for the endocannabinoid anandamide (AEA). Furthermore, animal studies by others have shown that elevated levels of endocannabinoids resulted in beneficial pharmacolog...

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Detalhes bibliográficos
Main Authors: Berger, William T., Ralph, Brian P., Kaczocha, Martin, Sun, Jing, Balius, Trent E., Rizzo, Robert C., Haj-Dahmane, Samir, Ojima, Iwao, Deutsch, Dale G.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3517626/
https://ncbi.nlm.nih.gov/pubmed/23236415
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0050968
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