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A Cell Permeable NPE Caged ADP-Ribose for Studying TRPM2

Transient potential receptor melastatin-2 (TRPM2) is a non-selective Ca(2+)-permeable cation channel of the TRPM channel subfamily and is mainly activated by intracellular adenosine diphosphate ribose (ADPR). Here we synthesized a 1-(2-nitrophenyl)ethyl caged ADPR (NPE-ADPR) and found that uncaging...

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Detalhes bibliográficos
Main Authors: Yu, Peilin, Wang, Qian, Zhang, Li-He, Lee, Hon-Cheung, Zhang, Liangren, Yue, Jianbo
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3517590/
https://ncbi.nlm.nih.gov/pubmed/23236422
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0051028
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