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Simultaneous Optical Recording in Multiple Cells by Digital Holographic Microscopy of Chloride Current Associated to Activation of the Ligand-Gated Chloride Channel GABA(A) Receptor

Chloride channels represent a group of targets for major clinical indications. However, molecular screening for chloride channel modulators has proven to be difficult and time-consuming as approaches essentially rely on the use of fluorescent dyes or invasive patch-clamp techniques which do not lend...

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Detalhes bibliográficos
Main Authors: Jourdain, Pascal, Boss, Daniel, Rappaz, Benjamin, Moratal, Corinne, Hernandez, Maria-Clemencia, Depeursinge, Christian, Magistretti, Pierre Julius, Marquet, Pierre
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3517575/
https://ncbi.nlm.nih.gov/pubmed/23236427
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0051041
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