Long-term effects of cranial irradiation and intrathecal chemotherapy in treatment of childhood leukemia: a MEG study of power spectrum and correlated cognitive dysfunction

BACKGROUND: Prophylaxis to prevent relapses in the central nervous system after childhood acute lymphoblastic leukemia (ALL) used to consist of both intrathecal chemotherapy (CT) and cranial irradiation (CRT). CRT was mostly abolished in the eighties because of its neurotoxicity, and replaced with m...

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Detalhes bibliográficos
Main Authors: Daams, Marita, Schuitema, Ilse, van Dijk, Bob W, van Dulmen-den Broeder, Eline, Veerman, Anjo JP, van den Bos, Cor, de Sonneville, Leo MJ
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2012
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Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3517522/
https://ncbi.nlm.nih.gov/pubmed/22928913
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2377-12-84
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