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Up-regulation of platelet-derived growth factor-A is responsible for the failure of re-initiated interferon alpha treatment in hepatocellular carcinoma

BACKGROUND: Postoperative interferon-α(IFN-α) treatment delays hepatocellular carcinoma(HCC) recurrence and prolongs patient survival, and may thus be an effective form of adjuvant therapy. However, clinical observations found that HCC recurs in some patients within 8 months of IFN-α treatment being...

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Autors principals: Zhang, Ju-Bo, Sun, Hui-Chuan, Jia, Wei-Dong, Zhuang, Peng-Yuan, Qian, Yong-Bing, Zhu, Xiao-Dong, Kong, Ling-Qun, Wang, Lu, Wu, Wei-Zhong, Tang, Zhao-You
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2012
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3517454/
https://ncbi.nlm.nih.gov/pubmed/23025904
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2407-12-439
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