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Aquaporin 3 (AQP3) participates in the cytotoxic response to nucleoside-derived drugs

BACKGROUND: Nucleoside analogs used in the chemotherapy of solid tumors, such as the capecitabine catabolite 5(′)-deoxy-5-fluorouridine (5(′)-DFUR) trigger a transcriptomic response that involves the aquaglyceroporin aquaporin 3 along with other p53-dependent genes. Here, we examined whether up-regu...

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Autors principals: Pérez-Torras, Sandra, Casado, F Javier, Pastor-Anglada, Marçal
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2012
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3517434/
https://ncbi.nlm.nih.gov/pubmed/23017148
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2407-12-434
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