Association of genetic variation in the NR1H4 gene, encoding the nuclear bile acid receptor FXR, with inflammatory bowel disease

BACKGROUND: Pathogenesis of inflammatory bowel diseases (IBD), ulcerative colitis (UC) and Crohn’s disease (CD), involves interaction between environmental factors and inappropriate immune responses in the intestine of genetically predisposed individuals. Bile acids and their nuclear receptor, FXR,...

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Detalhes bibliográficos
Main Authors: Attinkara, Ragam, Mwinyi, Jessica, Truninger, Kaspar, Regula, Jaroslaw, Gaj, Pawel, Rogler, Gerhard, Kullak-Ublick, Gerd A, Eloranta, Jyrki J
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2012
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3517390/
https://ncbi.nlm.nih.gov/pubmed/22929053
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1756-0500-5-461
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