Krüppel-like zinc finger proteins in end-stage COPD lungs with and without severe alpha1-antitrypsin deficiency

BACKGROUND: Chronic obstructive pulmonary disease (COPD) is influenced by environmental and genetic factors. An important fraction of COPD cases harbor a major genetic determinant, inherited ZZ (Glu342Lys) α1-antitrypsin deficiency (AATD). A study was undertaken to investigate gene expression patter...

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Autori principali: Koczulla, A-Rembert, Jonigk, Danny, Wolf, Thomas, Herr, Christian, Noeske, Sarah, Klepetko, Walter, Vogelmeier, Claus, von Neuhoff, Nils, Rische, Johanna, Wrenger, Sabine, Golpon, Heiko, Voswinckel, Robert, Luisetti, Maurizio, Ferrarotti, Ilaria, Welte, Tobias, Janciauskiene, Sabina
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2012
Soggetti:
Research
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3517304/
https://ncbi.nlm.nih.gov/pubmed/22621770
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1750-1172-7-29
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