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Single-Cell Network Profiling of Peripheral Blood Mononuclear Cells from Healthy Donors Reveals Age- and Race-Associated Differences in Immune Signaling Pathway Activation

A greater understanding of the function of the human immune system at the single-cell level in healthy individuals is critical for discerning aberrant cellular behavior that occurs in settings such as autoimmunity, immunosenescence, and cancer. To achieve this goal, a systems-level approach capable...

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Detalhes bibliográficos
Main Authors: Longo, Diane M., Louie, Brent, Putta, Santosh, Evensen, Erik, Ptacek, Jason, Cordeiro, James, Wang, Ena, Pos, Zoltan, Hawtin, Rachael E., Marincola, Francesco M., Cesano, Alessandra
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3517183/
https://ncbi.nlm.nih.gov/pubmed/22246624
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1102514
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