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The Effects of Acrolein on the Thioredoxin System: Implications for Redox-Sensitive Signaling

The reactive aldehyde acrolein is a ubiquitous environmental pollutant and is also generated endogenously. It is a strong electrophile and reacts rapidly with nucleophiles including thiolates. This review focuses on the effects of acrolein on thioredoxin reductase (TrxR) and thioredoxin (Trx), which...

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Detalhes bibliográficos
Main Authors: Myers, Charles R., Myers, Judith M., Kufahl, Timothy D., Forbes, Rachel, Szadkowski, Adam
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3517082/
https://ncbi.nlm.nih.gov/pubmed/21812108
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/mnfr.201100224
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