The incidence of pancreatic cancer in BRCA1 and BRCA2 mutation carriers

BACKGROUND: Germline mutations in BRCA1 and BRCA2 predispose to pancreatic cancer. We estimated the incidence of pancreatic cancer in a cohort of female carriers of BRCA1 and BRCA2 mutation. We also estimated survival rates in pancreatic cancer cases from families with a BRCA mutation. METHODS: We f...

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Hlavní autoři: Iqbal, J, Ragone, A, Lubinski, J, Lynch, H T, Moller, P, Ghadirian, P, Foulkes, W D, Armel, S, Eisen, A, Neuhausen, S L, Senter, L, Singer, C F, Ainsworth, P, Kim-Sing, C, Tung, N, Friedman, E, Llacuachaqui, M, Ping, S, Narod, S A
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group 2012
Témata:
Genetics & Genomics
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3516682/
https://ncbi.nlm.nih.gov/pubmed/23099806
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/bjc.2012.483
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