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Antibody to the Filarial Antigen Wb123 Reflects Reduced Transmission and Decreased Exposure in Children Born following Single Mass Drug Administration (MDA)

BACKGROUND: Antibody (Ab) to the Wuchereria bancrofti (Wb) infective larval (L3) antigen Wb123, using a Luciferase Immunoprecipitation System (LIPS) assay, has been shown to be a species-specific, early marker of infection developed for potential use as a surveillance tool following transmission int...

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Autors principals: Steel, Cathy, Kubofcik, Joseph, Ottesen, Eric A., Nutman, Thomas B.
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2012
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3516579/
https://ncbi.nlm.nih.gov/pubmed/23236533
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pntd.0001940
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