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MiniCD4 Microbicide Prevents HIV Infection of Human Mucosal Explants and Vaginal Transmission of SHIV(162P3) in Cynomolgus Macaques
In complement to an effective vaccine, development of potent anti-HIV microbicides remains an important priority. We have previously shown that the miniCD4 M48U1, a functional mimetic of sCD4 presented on a 27 amino-acid stable scaffold, inhibits a broad range of HIV-1 isolates at sub-nanomolar conc...
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Main Authors: | , , , , , , , , , , , , , , |
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格式: | Artigo |
語言: | Inglês |
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Public Library of Science
2012
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在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3516572/ https://ncbi.nlm.nih.gov/pubmed/23236282 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1003071 |
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