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HIV-1 Expressing the Envelopes of Transmitted/Founder or Control/Reference Viruses Have Similar Infection Patterns of CD4 T-Cells in Human Cervical Tissue Ex Vivo

Recently, it was found that 80% of sexual HIV-1 transmissions are established by a single virion/viral genome. To investigate whether the transmitted/founder (T/F) viruses have specific biological properties favoring sexual transmission, we inoculated human cervical tissue explants with isogenic HIV...

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Autori principali: Merbah, Melanie, Arakelyan, Anush, Edmonds, Tara, Ochsenbauer, Christina, Kappes, John C., Shattock, Robin J., Grivel, Jean-Charles, Margolis, Leonid B.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2012
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3516523/
https://ncbi.nlm.nih.gov/pubmed/23236398
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0050839
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