Cadherin point mutations alter cell sorting and modulate GTPase signaling

This study investigated the impact of cadherin binding differences on both cell sorting and GTPase activation. The use of N-terminal domain point mutants of Xenopus C-cadherin enabled us to quantify binding differences and determine their effects on cadherin-dependent functions without any potential...

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Detalhes bibliográficos
Main Authors: Tabdili, Hamid, Barry, Adrienne K., Langer, Matthew D., Chien, Yuan-Hung, Shi, Quanming, Lee, Keng Jin, Lu, Shaoying, Leckband, Deborah E.
Formato: Artigo
Idioma:Inglês
Publicado em: The Company of Biologists 2012
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3516376/
https://ncbi.nlm.nih.gov/pubmed/22505612
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/jcs.087395
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