Preferential accumulation within tumors and in vivo imaging by functionalized luminescent dendrimer lanthanide complexes

We have created a dendrimer complex suitable for preferential accumulation within liver tumors and luminescence imaging by substituting thirty-two naphthalimide fluorophores on the surface of the dendrimer and incorporating eight europium cations within the branches. We demonstrate the utility and p...

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Bibliografiske detaljer
Main Authors: Alcala, Marco A., Shade, Chad M., Uh, Hyounsoo, Kwan, Shu Ying, Bischof, Matthias, Thompson, Zachary P., Gogick, Kristy A., Meier, Adam R., Strein, Timothy G., Bartlett, David L., Modzelewski, Ruth A., Lee, Yong J., Petoud, Stéphane, Brown, Charles Komen
Format: Artigo
Sprog:Inglês
Udgivet: 2011
Fag:
Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3515843/
https://ncbi.nlm.nih.gov/pubmed/21925728
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.biomaterials.2011.07.076
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