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ATPase-dependent role of the atypical kinase Rio2 on the evolving pre-40S subunit
Ribosome synthesis involves dynamic association of ribosome biogenesis factors with evolving pre-ribosomal particles. Rio2 is an atypical protein kinase required for pre-40S subunit maturation. We report the crystal structure of eukaryotic Rio2 with bound ATP/Mg(2+). Unexpectedly, the structure reve...
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| Main Authors: | , , , , , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2012
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3515705/ https://ncbi.nlm.nih.gov/pubmed/23104056 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nsmb.2403 |
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