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A Single Lys Residue on the First Intracellular Loop Modulates the Endoplasmic Reticulum Export and Cell-Surface Expression of α(2A)-Adrenergic Receptor

Export from the endoplasmic reticulum (ER) represents an initial step in intracellular trafficking of G protein-coupled receptors (GPCRs). However, the underlying molecular mechanisms remain poorly understood. We have previously demonstrated that a highly conserved Leu residue on the first intracell...

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Detalhes bibliográficos
Main Authors: Fan, Yi, Li, Chunman, Guo, Jianhui, Hu, Gang, Wu, Guangyu
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3515576/
https://ncbi.nlm.nih.gov/pubmed/23227171
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0050416
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