Macrophages Facilitate Coal Tar Pitch Extract-Induced Tumorigenic Transformation of Human Bronchial Epithelial Cells Mediated by NF-κB

OBJECTIVE: Chronic respiratory inflammation has been associated with lung cancer. Tumor-associated macrophages (TAMs) play a critical role in the formation of inflammation microenvironment. We sought to characterize the role of TAMs in coal tar pitch extract (CTPE)-induced tumorigenic transformation...

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Autors principals: Feng, Feifei, Wu, Yiming, Zhang, Shaofeng, Liu, Yu, Qin, Lijuan, Wu, Yongjun, Yan, Zhen, Wu, Weidong
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2012
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3515562/
https://ncbi.nlm.nih.gov/pubmed/23227270
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0051690
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