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Identification of Regions Involved in Substrate Binding and Dimer Stabilization within the Central Domains of Yeast Hsp40 Sis1

Protein folding, refolding and degradation are essential for cellular life and are regulated by protein homeostatic processes such those that involve the molecular chaperone DnaK/Hsp70 and its co-chaperone DnaJ. Hsp70 action is initiated when proteins from the DnaJ family bind an unfolded protein fo...

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Detalhes bibliográficos
Main Authors: Borges, Júlio C., Seraphim, Thiago V., Mokry, David Z., Almeida, Fabio C. L., Cyr, Douglas M., Ramos, Carlos H. I.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3515540/
https://ncbi.nlm.nih.gov/pubmed/23227221
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0050927
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