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The FOP Metamorphogene Encodes a Novel Type I Receptor That Dysregulates BMP Signaling

The ability of mature organisms to stabilize phenotypes has enormous selective advantage across all phyla, but the mechanisms have been largely unexplored. Individuals with fibrodysplasia ossificans progressiva (FOP), a rare genetic disorder of progressive heterotopic ossification, undergo a patholo...

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Autors principals: Kaplan, Frederick S., Pignolo, Robert J., Shore, Eileen M.
Format: Artigo
Idioma:Inglês
Publicat: 2009
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3515059/
https://ncbi.nlm.nih.gov/pubmed/19896889
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cytogfr.2009.10.006
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