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Mechanisms of histone H3 lysine 27 trimethylation remodeling during early mammalian development

During fertilization, two of the most differentiated cells in the mammalian organism, a sperm and oocyte, are combined to form a pluripotent embryo. Dynamic changes in chromatin structure allow the transition of the chromatin on these specialized cells into an embryonic configuration capable of gene...

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Autori principali: Bogliotti, Yanina S., Ross, Pablo J.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Landes Bioscience 2012
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3515017/
https://ncbi.nlm.nih.gov/pubmed/22895114
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/epi.21615
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