Prognostic significance of AKT/mTOR signaling in advanced neuroendocrine tumors treated with somatostatin analogs

INTRODUCTION: Somatostatin analogs (SSAs) are used as part of standard treatment for advanced neuroendocrine tumors (NETs). The mechanisms behind the antiproliferative action of SSAs remain largely unknown, but a connection with the mammalian target of rapamycin (mTOR) signaling pathway has been sug...

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Detalhes bibliográficos
Main Authors: Fernandes, Isabel, Pacheco, Teresa R, Costa, Adília, Santos, Ana C, Fernandes, Ana R, Santos, Mara, Oliveira, António G, Casimiro, Sandra, Quintela, António, Fernandes, Afonso, Ramos, Madalena, Costa, Luís
Formato: Artigo
Idioma:Inglês
Publicado em: Dove Medical Press 2012
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Original Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3514972/
https://ncbi.nlm.nih.gov/pubmed/23226698
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/OTT.S36330
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