NMDA Receptor-Dependent Afterdepolarizations Are Curtailed by Carbonic Anhydrase 14: Regulation of a Short-Term Postsynaptic Potentiation

In the hippocampus, extracellular carbonic anhydrase (Car) speeds the buffering of an activity-generated rise in extracellular pH that impacts H(+)-sensitive NMDA receptors (NMDARs). We studied the role of Car14 in this brain structure, in which it is expressed solely on neurons. Current-clamp respo...

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Detalhes bibliográficos
Main Authors: Makani, Sachin, Chen, Huei-Ying, Esquenazi, Susana, Shah, Gul N., Waheed, Abdul, Sly, William S., Chesler, Mitchell
Formato: Artigo
Idioma:Inglês
Publicado em: Society for Neuroscience 2012
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Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3514870/
https://ncbi.nlm.nih.gov/pubmed/23175829
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.1467-12.2012
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