Epithelial-to-Mesenchymal Transition in Pancreatic Ductal Adenocarcinoma and Pancreatic Tumor Cell Lines: The Role of Neutrophils and Neutrophil-Derived Elastase

Pancreatic ductal adenocarcinoma (PDAC) is frequently associated with fibrosis and a prominent inflammatory infiltrate in the desmoplastic stroma. Moreover, in PDAC, an epithelial-to-mesenchymal transition (EMT) is observed. To explore a possible connection between the infiltrating cells, particular...

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Autors principals: Große-Steffen, Thomas, Giese, Thomas, Giese, Nathalia, Longerich, Thomas, Schirmacher, Peter, Hänsch, G. Maria, Gaida, Matthias M.
Format: Artigo
Idioma:Inglês
Publicat: Hindawi Publishing Corporation 2012
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3514849/
https://ncbi.nlm.nih.gov/pubmed/23227088
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2012/720768
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