Development of a Flow Cytometry Live Cell Assay for the Screening of Inhibitors of Hepatitis C Virus (HCV) Replication

In this study, we established a flow cytometry live cell-based assay that permits the screening of hepatitis C virus (HCV) inhibitors. Specifically, we created a stable cell line, which harbors a subgenomic replicon encoding an NS5A-YFP fusion protein. This system allows direct measurement of YFP fl...

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Bibliographic Details
Main Authors: Garcia-Rivera, Jose A, Lin, Kai, Hopkins, Sam, Gregory, Matthew A, Wilkinson, Barrie, Gallay, Philippe A
Format: Artigo
Language:Inglês
Published: Bentham Open 2012
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3514710/
https://ncbi.nlm.nih.gov/pubmed/23230455
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2174/1874357901206010097
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