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Failure of chlorpromazine to inhibit fluid accumulation caused by Escherichia coli heat-stable enterotoxin in suckling mice.

We studied the effect of chlorpromazine on fluid accumulation caused by purified heat-stable enterotoxin (ST) from enterotoxigenic Escherichia coli in suckling mice. We found that chlorpromazine inactivated ST itself in vitro, but did not inhibit the activity of ST in the intestines.

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Detalles Bibliográficos
Publicado en:Infect Immun
Main Authors: Takeda, T, Honda, T, Takeda, Y, Miwatani, T
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Microbiology (ASM) 1981
Assuntos:
Acceso en liña:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC351470/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7195875/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/iai.32.2.480-483.1981
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