Complex DNA repair pathways as possible therapeutic targets to overcome temozolomide resistance in glioblastoma

Many conventional chemotherapeutic drugs exert their cytotoxic function by inducing DNA damage in the tumor cell. Therefore, a cell-inherent DNA repair pathway, which reverses the DNA-damaging effect of the cytotoxic drugs, can mediate therapeutic resistance to chemotherapy. The monofunctional DNA-a...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Main Authors: Yoshimoto, Koji, Mizoguchi, Masahiro, Hata, Nobuhiro, Murata, Hideki, Hatae, Ryusuke, Amano, Toshiyuki, Nakamizo, Akira, Sasaki, Tomio
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2012
Assuntos:
Oncology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3514620/
https://ncbi.nlm.nih.gov/pubmed/23227453
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fonc.2012.00186
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados