Učitavanje...
Complex DNA repair pathways as possible therapeutic targets to overcome temozolomide resistance in glioblastoma
Many conventional chemotherapeutic drugs exert their cytotoxic function by inducing DNA damage in the tumor cell. Therefore, a cell-inherent DNA repair pathway, which reverses the DNA-damaging effect of the cytotoxic drugs, can mediate therapeutic resistance to chemotherapy. The monofunctional DNA-a...
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| Glavni autori: | , , , , , , , |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
Frontiers Media S.A.
2012
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| Teme: | |
| Online pristup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3514620/ https://ncbi.nlm.nih.gov/pubmed/23227453 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fonc.2012.00186 |
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