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Highly efficient binding of paramagnetic beads bioconjugated with 100,000 or more antibodies to protein-coated surfaces

We report here the first kinetic characterization of 1 μm super diameter paramagnetic particles (MP) decorated with over 100,000 antibodies binding to protein antigens attached to flat surfaces. Surface plasmon resonance (SPR) was used to show that these antibody-derivatized MPs (MP-Ab(2)) exhibit i...

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Autors principals: Mani, Vigneshwaran, Wasalathanthri, Dhanuka P., Joshi, Amit A., Kumar, Challa V., Rusling, James F.
Format: Artigo
Idioma:Inglês
Publicat: 2012
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3514570/
https://ncbi.nlm.nih.gov/pubmed/23121341
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ac3028257
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