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MCMC Can Detect Nonidentifiable Models

Continuous-time Markov models have been considered the best representation for the stochastic dynamics of ion channels for more than thirty years. For most single-channel data sets, several open and closed states are required for accurately representing the dynamics. However, each data point only sh...

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Bibliographic Details
Main Authors: Siekmann, Ivo, Sneyd, James, Crampin, Edmund J.
Format: Artigo
Language:Inglês
Published: The Biophysical Society 2012
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3514526/
https://ncbi.nlm.nih.gov/pubmed/23283226
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2012.10.024
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