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Beckwith Wiedemann imprinting defect found in leucocyte but not buccal DNA in a child born small for gestational age

BACKGROUND: Loss of methylation (LOM) at imprinting control region (ICR) 1 or LOM at ICR 2 on chromosome 11p15 in leucocyte DNA is commonly used to diagnose the imprinting disorders Silver Russell syndrome (SRS) characterized by growth restriction or Beckwith Wiedemann syndrome (BWS) characterized b...

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Bibliografski detalji
Glavni autori: Murphy, Rinki, Mackay, Deborah, Mitchell, Ed A
Format: Artigo
Jezik:Inglês
Izdano: BioMed Central 2012
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3514203/
https://ncbi.nlm.nih.gov/pubmed/23116464
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2350-13-99
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