Adoptive cell therapy with autologous tumor infiltrating lymphocytes and low-dose Interleukin-2 in metastatic melanoma patients

BACKGROUND: Adoptive cell therapy may be based on isolation of tumor-specific T cells, e.g. autologous tumor infiltrating lymphocytes (TIL), in vitro activation and expansion and the reinfusion of these cells into patients upon chemotherapy induced lymphodepletion. Together with high-dose interleuki...

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Bibliographic Details
Main Authors: Ellebaek, Eva, Iversen, Trine Zeeberg, Junker, Niels, Donia, Marco, Engell-Noerregaard, Lotte, Met, Özcan, Hölmich, Lisbet Rosenkrantz, Andersen, Rikke Sick, Hadrup, Sine Reker, Andersen, Mads Hald, thor Straten, Per, Svane, Inge Marie
Format: Artigo
Language:Inglês
Published: BioMed Central 2012
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Research
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3514199/
https://ncbi.nlm.nih.gov/pubmed/22909342
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1479-5876-10-169
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