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Association of radiotherapy with preferential depletion of luminal epithelial cells in a BRCA1 mutation carrier

Radiation therapy (RT) after breast conservation therapy has recently been linked with significant reduction in risk of ipsilateral breast cancer among BRCA1 mutation carriers. However, the exact mechanism by which RT reduces incidence of BRCA1-associated cancer remains unclear. Here we studied fres...

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Bibliografske podrobnosti
Main Authors: Chiang, Huai-Chin, Nair, Sreejith J, Yeh, I-Tien, Santillan, Alfredo A, Hu, Yanfen, Elledge, Richard, Li, Rong
Format: Artigo
Jezik:Inglês
Izdano: BioMed Central 2012
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3514114/
https://ncbi.nlm.nih.gov/pubmed/23210696
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/2162-3619-1-31
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