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Hedgehog is required for CySC self-renewal but does not contribute to the GSC niche in the Drosophila testis

The Drosophila testis harbors two types of stem cells: germ line stem cells (GSCs) and cyst stem cells (CySCs). Both stem cell types share a physical niche called the hub, located at the apical tip of the testis. The niche produces the JAK/STAT ligand Unpaired (Upd) and BMPs to maintain CySCs and GS...

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Autori principali: Amoyel, Marc, Sanny, Justina, Burel, Michael, Bach, Erika A.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Company of Biologists 2013
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3513992/
https://ncbi.nlm.nih.gov/pubmed/23175633
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dev.086413
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