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Small molecule inhibitors of ezrin inhibit the invasive phenotype of osteosarcoma cells
Ezrin is a multifunctional protein that connects the actin cytoskeleton to the extracellular matrix through transmembrane proteins. High ezrin expression is associated with lung metastasis and poor survival in cancer. We screened small molecule libraries for compounds that directly interact with ezr...
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| Main Authors: | , , , , , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3513970/ https://ncbi.nlm.nih.gov/pubmed/21706056 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/onc.2011.245 |
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