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Models of Crk Adaptor Proteins in Cancer
The Crk family of adaptor proteins (CrkI, CrkII, and CrkL), originally discovered as the oncogene fusion product, v-Crk, of the CT10 chicken retrovirus, lacks catalytic activity but engages with multiple signaling pathways through their SH2 and SH3 domains. Crk proteins link upstream tyrosine kinase...
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
SAGE Publications
2012
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3513787/ https://ncbi.nlm.nih.gov/pubmed/23226572 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/1947601912459951 |
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