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(15)N-(1)H Scalar Coupling Perturbation: An Additional Probe for Measuring Structural Changes Due to Ligand Binding
Chemical shift perturbation mapping of backbone amides is one of the most widely employed techniques in biomolecular NMR, providing residue-by-residue information on interaction interfaces, ligand binding and chemical modification sites, even for samples where poor solubility, short lifetime, or lar...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
2009
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3513771/ https://ncbi.nlm.nih.gov/pubmed/19580276 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja903552q |
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