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Leptin and leptin receptor: Analysis of a structure to function relationship in interaction and evolution from humans to fish

Leptin is a circulating protein which regulates dietary intake through binding the leptin receptor. Numerous labs have used known structures and mutagenesis to study this binding process in common animal models (human, mouse and rat). Understanding this binding process in other vertebrate species wi...

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Detalhes bibliográficos
Main Authors: Prokop, JW, Duff, RJ, Ball, HC, Copeland, DL, Londraville, RL
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3513635/
https://ncbi.nlm.nih.gov/pubmed/23085324
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.peptides.2012.10.002
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