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The genomic landscape and evolutionary resolution of antagonistic pleiotropy in yeast

Antagonistic pleiotropy (AP) or genetic tradeoff is an important concept invoked frequently in theories of aging, cancer, genetic disease, and other common phenomena. But, it is unclear how prevalent AP is, which genes are subject to AP, and to what extent and how AP may be resolved. By measuring th...

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Autori principali: Qian, Wenfeng, Ma, Di, Xiao, Che, Wang, Zhi, Zhang, Jianzhi
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2012
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3513580/
https://ncbi.nlm.nih.gov/pubmed/23103169
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2012.09.017
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