Differing Effects of Rapamycin or Calcineurin Inhibitor on T-Regulatory Cells in Pediatric Liver and Kidney Transplant Recipients

In a cross-sectional study, we assessed effects of calcineurin inhibitor (CNI) or rapamycin on T-regulatory (Treg) cells from children with stable liver (n=53) or kidney (n=9) allografts several years post-transplant. We analyzed Treg number, phenotype, suppressive function, and methylation at the T...

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Autori principali: Akimova, Tatiana, Kamath, Binita M., Goebel, Jens W., Meyers, Kevin E. C., Rand, Elizabeth B., Hawkins, Andre, Levine, Matthew H., Bucuvalas, John C., Hancock, Wayne W.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2012
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3513508/
https://ncbi.nlm.nih.gov/pubmed/22994804
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1600-6143.2012.04269.x
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