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Antagonism between MES-4 and Polycomb Repressive Complex 2 Promotes Appropriate Gene Expression in C. elegans Germ Cells

The C. elegans MES proteins are key chromatin regulators of the germline. MES-2, MES-3, and MES-6 form the C. elegans Polycomb Repressive Complex 2 and generate repressive H3K27me3. MES-4 generates H3K36me3 on germline-expressed genes. Transcript profiling of dissected mutant germlines revealed that...

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Autors principals: Gaydos, Laura, Rechtsteiner, Andreas, Egelhofer, Thea, Carroll, Coleen, Strome, Susan
Format: Artigo
Idioma:Inglês
Publicat: 2012
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3513488/
https://ncbi.nlm.nih.gov/pubmed/23103171
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2012.09.019
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