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Preparation and Characterization of Stable pH-Sensitive Vesicles Composed of α-Tocopherol Hemisuccinate

The current study aims to develop a stable pH-sensitive drug delivery system. First, cleavable polyethylene glycol-α-tocopherol hemisuccinate (PEG-THS) was synthesized. Conventional pH-sensitive vesicles composed of the Tris salt of α-tocopherol hemisuccinate (THST) were then prepared using the dete...

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Detalhes bibliográficos
Main Authors: Xu, Huan, Deng, Yi-Hui, Wang, Kai-Qian, Chen, Da-Wei
Formato: Artigo
Idioma:Inglês
Publicado em: Springer US 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3513435/
https://ncbi.nlm.nih.gov/pubmed/23054989
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1208/s12249-012-9863-7
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