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High-Frequency Hippocampal Oscillations Activated by Optogenetic Stimulation of Transplanted Human ESC-Derived Neurons

After transplantation, individual stem cell-derived neurons can functionally integrate into the host CNS; however, evidence that neurons derived from transplanted human embryonic stem cells (hESCs) can drive endogenous neuronal network activity in CNS tissue is still lacking. Here, using multielectr...

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Autors principals: Piña-Crespo, Juan C., Talantova, Maria, Cho, Eun-Gyung, Soussou, Walid, Dolatabadi, Nima, Ryan, Scott D., Ambasudhan, Rajesh, McKercher, Scott, Deisseroth, Karl, Lipton, Stuart A.
Format: Artigo
Idioma:Inglês
Publicat: Society for Neuroscience 2012
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3513396/
https://ncbi.nlm.nih.gov/pubmed/23136422
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.3735-12.2012
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