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Smooth muscle cell–extrinsic vascular spasm arises from cardiomyocyte degeneration in sarcoglycan-deficient cardiomyopathy

Vascular spasm is a poorly understood but critical biomedical process because it can acutely reduce blood supply and tissue oxygenation. Cardiomyopathy in mice lacking γ-sarcoglycan or δ-sarcoglycan is characterized by focal damage. In the heart, sarcoglycan gene mutations produce regional defects i...

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Detalhes bibliográficos
Main Authors: Wheeler, Matthew T., Allikian, Michael J., Heydemann, Ahlke, Hadhazy, Michele, Zarnegar, Sara, McNally, Elizabeth M.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 2004
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC351323/
https://ncbi.nlm.nih.gov/pubmed/14991064
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI200420410
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