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260 Association Between Genetic Polymorphisms of ABCC2 Transporter and the Susceptibility to Maculopapular Eruption Induced by Antituberculosis Drugs

BACKGROUND: ATP-binding cassette (ABC) transporter proteins play an important role in drug disposition. Polymorphisms of ABC transporter genes (ABCC2 and ABCB1) may be risk markers for maculopapular eruption (MPE) induced by unusual accumulation of antituberculosis drugs (ATD) itself or metabolites....

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Bibliographic Details
Main Authors: Kim, Sang-Hoon, Kim, Sang-Heon, Lee, Jae-Hyung, Lee, Byoung-Hoon, Jee, Young-Koo
Format: Artigo
Language:Inglês
Published: World Allergy Organization Journal 2012
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3512837/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/01.WOX.0000412017.99479.f7
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