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Genomic evidence for elevated mutation rates in highly expressed genes
Reporter gene assays have demonstrated both transcription-associated mutagenesis (TAM) and transcription-coupled repair, but the net impact of transcription on mutation rate remains unclear, especially at the genomic scale. Using comparative genomics of related species as well as mutation accumulati...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
European Molecular Biology Organization
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3512408/ https://ncbi.nlm.nih.gov/pubmed/23146897 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/embor.2012.165 |
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