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Intervertebral disc degeneration: evidence for two distinct phenotypes

We review the evidence that there are two types of disc degeneration. ‘Endplate-driven’ disc degeneration involves endplate defects and inwards collapse of the annulus, has a high heritability, mostly affects discs in the upper lumbar and thoracic spine, often starts to develop before age 30 years,...

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Detalhes bibliográficos
Main Authors: Adams, Michael A, Dolan, Patricia
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Science Inc 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3512277/
https://ncbi.nlm.nih.gov/pubmed/22881295
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1469-7580.2012.01551.x
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