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Structure–Function Dissection of the Frizzled Receptor in Drosophila melanogaster Suggests Different Mechanisms of Action in Planar Polarity and Canonical Wnt Signaling

Members of the Frizzled family of sevenpass transmembrane receptors signal via the canonical Wnt pathway and also via noncanonical pathways of which the best characterized is the planar polarity pathway. Activation of both canonical and planar polarity signaling requires interaction between Frizzled...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Strutt, David, Madder, Daisy, Chaudhary, Varun, Artymiuk, Peter J.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Genetics Society of America 2012
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC3512140/
https://ncbi.nlm.nih.gov/pubmed/23023003
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1534/genetics.112.144592
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