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Kaposi Sarcoma Herpesvirus Promotes Endothelial-to-Mesenchymal Transition through Notch-Dependent Signaling

Endothelial-to-mesenchymal transition (EndMT) is now widely considered a pivotal contributor to cancer progression. In this study, we show that the Kaposi’s sarcoma (KS)–associated herpesvirus (KSHV) is a sufficient cause of EndMT, potentially helping to explain the aggressiveness of KS that occurs...

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Detalhes bibliográficos
Main Authors: Gasperini, Paola, Espigol-Frigole, Georgina, McCormick, Peter J., Salvucci, Ombretta, Maric, Dragan, Uldrick, Thomas S., Polizzotto, Mark N., Yarchoan, Robert, Tosato, Giovanna
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3512101/
https://ncbi.nlm.nih.gov/pubmed/22237624
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-11-3067
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